Adaptive design has become an important tool in modern pharmaceutical research and development. Compared to a classic trial design with static features, an adaptive design allows for the modification of the characteristics of ongoing trials based on cumulative information. Adaptive designs increase the probability of success, reduce costs and the time to market, and promote accurate drug delivery to patients. Reflecting the state of the art in adaptive design approaches, Adaptive Design Theory and Implementation Using SAS ...
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Adaptive design has become an important tool in modern pharmaceutical research and development. Compared to a classic trial design with static features, an adaptive design allows for the modification of the characteristics of ongoing trials based on cumulative information. Adaptive designs increase the probability of success, reduce costs and the time to market, and promote accurate drug delivery to patients. Reflecting the state of the art in adaptive design approaches, Adaptive Design Theory and Implementation Using SAS and R provides a concise, unified presentation of adaptive design theories, uses SAS and R for the design and simulation of adaptive trials, and illustrates how to master different adaptive designs through real-world examples. The book focuses on simple two-stage adaptive designs with sample size re-estimation before moving on to explore more challenging designs and issues that include drop-loser, adaptive dose-funding, biomarker-adaptive, multiple-endpoint adaptive, response-adaptive randomization, and Bayesian adaptive designs. In many of the chapters, the author compares methods and provides practical examples of the designs, including those used in oncology, cardiovascular, and inflammation trials. Equipped with the knowledge of adaptive design presented in this book, you will be able to improve the efficiency of your trial design, thereby reducing the time and cost of drug development.
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Add this copy of Adaptive Design Theory and Implementation Using Sas and to cart. $19.75, very good condition, Sold by Michael Knight, Bookseller rated 4.0 out of 5 stars, ships from Forest Grove, OR, UNITED STATES, published 2014 by Chapman and Hall/CRC.
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New. Print on demand Contains: Illustrations, black & white, Tables, black & white. Chapman & Hall/CRC Biostatistics Series . Includes: tables, black & white, illustrations, black & white. Intended for professional and scholarly audience.
Add this copy of Adaptive Design Theory and Implementation Using Sas and to cart. $81.80, new condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Santa Clarita, CA, UNITED STATES, published 2007 by Chapman and Hall/CRC.
Add this copy of Adaptive Design Theory and Implementation Using Sas and to cart. $82.00, very good condition, Sold by BookHouse On-Line rated 5.0 out of 5 stars, ships from Minneapolis, MN, UNITED STATES, published 2014 by Chapman and Hall/CRC.
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Very Good. No Dust Jacket Issued. Size: 9x6x1; 2nd edition. Text unmarked and clean, pages bright. Binding is tight, sturdy, and square. Bumping to head of spine, light bumping to bottom outer corner, otherwise shelfwear is very minor. Ships same or next business day from Dinkytown in Minneapolis, Minnesota. Due to the size/weight of this book extra charges may apply for international shipping.
