Advances and Technical Standards in Neurosurgery: Volume 34

Advances and Technical Standards in Neurosurgery was conceived in 1972byitsfoundingfathersJeanBrihaye, BernardPertuiset, FritzLoew andHugoKrayenbuuhlatacombinedmeetingoftheItalianandGerman NeurosurgicalSocietiesinTaormina. Itwasdesignedtocomplementthe Europeanpost-graduatetrainingsystemforyoungneurosurgeonsandwas ?rst published in 1974 initially through sponsorship by the European AssociationofNeurosurgicalSocieties. Allcontributionshavebeenp- lishedinEnglishtofacilitateinternationalunderstanding. ... Read More

Advances and Technical Standards in Neurosurgery was conceived in 1972byitsfoundingfathersJeanBrihaye, BernardPertuiset, FritzLoew andHugoKrayenbuuhlatacombinedmeetingoftheItalianandGerman NeurosurgicalSocietiesinTaormina. Itwasdesignedtocomplementthe Europeanpost-graduatetrainingsystemforyoungneurosurgeonsandwas ?rst published in 1974 initially through sponsorship by the European AssociationofNeurosurgicalSocieties. Allcontributionshavebeenp- lishedinEnglishtofacilitateinternationalunderstanding. Theambitionofallsuccessiveeditorialboardshasbeentoprovidean opportunityformaturescholarshipandre?ection, notconstrainedbyar- ?ciallimitsonspace. Theseriesprovidesaremarkableaccountofprogress overthepast35years, bothwithregardtoadvances, detaileddescriptions of standard operative procedures and in- depth reviews of established knowledge. Thepresentvolumeisnoexceptionandshouldappealtoboth experiencedneurosurgeonsandyoungneurosurgeonsintrainingalike. TheEditors Contents Listofcontributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XIII Advances Present and potential future adjuvant issues in high-grade astrocytic glioma 1,2 1 1 2 1 treatment. F. LEFRANC, M. RYNKOWSKI, O. DEWITTE, andR. KISS, Department ofNeurosurgery, ErasmeUniversityHospital, FreeUniversityofBrussels(U. L. B. ), 2 Brussels, Belgium, LaboratoryofToxicology, InstituteofPharmacy, FreeUniversity ofBrussels(U. L. B. ), Brussels, Belgium Abstract. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Naturalresistanceofmigratingmalignantgliomacellstoapoptosis (radiotherapyandchemotherapy). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Patternsofcelldeath. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Autophagy: apotentialTrojanhorseformalignantgliomas. . . . . . . . . . . . . . . . 11 Therapeuticbene?tsoftemozolomide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Localtherapiesforglioblastomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Ongoingclinicaltrialsforglioblastomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Growthfactorreceptorinhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 PI3K=Akt, mTORandNF- Binhibitors. . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Matrixmetalloproteinase(MMP)inhibitors(MMPI). . . . . . . . . . . . . . . . . . . 18 Angiogenesistargeting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Cellularandvaccinationtherapies. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Genetherapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Reducingmalignantgliomacellmotilityinordertorestore pro-apoptoticdrugsensitivity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Thesodiumpumpconstitutesapotentialtargettocombat malignantgliomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Thesodiumpump. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Cardiotonicsteroids: ligandsofthesodiumpump. . . . . . . . . . . . . . . . . . . . 24 VIII Contents Thesodiumpumpisinvolvedincancercellproliferation, migrationanddeath. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Braintumorstemcellsapotentialtargettocombatmalignantgliomas. . . . . . . 26 Conclusions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Deepbrainstimulationforpsychiatricdisorders stateoftheart. T. E. SCHLA APFER and B. H. BEWERNICK, Brain Stimulation Group, Departm Read Less

• All from $149.67
• New Books from $151.18
• Used Books from $149.67
• Rare Books from $151.19

• All Copies (6)
• Softcover (1)
• Hardcover (5)
• Choose Edition (2)

• Book Details
• Seller
• Sort Seller Rating Price: Low to High Price: High to Low Condition Condition: Reverse Pub Date Pub Date: Reverse

• Hardcover, Fine/Like New 2009, Springer ISBN-13: 9783211787403 See Item Details ▾

  GreatBookPrices HIGH Columbia, MD, USA

  $149.67 $240.00 Add to Cart Add this copy of Advances and Technical Standards in Neurosurgery: to cart. $149.67, like new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2009 by Springer.

  	Edition: 2009, Springer Hardcover, Fine/Like New Available Copies: 2	Details: ISBN: 3211787402 ISBN-13: 9783211787403 Pages: 209 Edition: 2009 edition Publisher: Springer Published: 2009 Language: English Alibris ID: 18306178833	Shipping Options: Standard Shipping: $4.99 Choose your shipping method in Checkout. Costs may vary based on destination.
  Seller's Description: Fine. Sewn binding. Paper over boards. 209 p. Contains: Illustrations, black & white, Illustrations, color, Line drawings, black & white, Line drawings, color, Tables, black & white, Figures. Advances and Technical Standards in Neurosurgery, 34. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
  ► Contact This Seller
  Hide Details ▴

• Hardcover, New 2009, Springer ISBN-13: 9783211787403 See Item Details ▾

  GreatBookPrices HIGH Columbia, MD, USA

  $151.18 $240.00 Add to Cart Add this copy of Advances and Technical Standards in Neurosurgery: to cart. $151.18, new condition, Sold by GreatBookPrices rated 4.0 out of 5 stars, ships from Columbia, MD, UNITED STATES, published 2009 by Springer.

  	Edition: 2009, Springer Hardcover, New Available Copies: 2	Details: ISBN: 3211787402 ISBN-13: 9783211787403 Pages: 209 Edition: 2009 edition Publisher: Springer Published: 2009 Language: English Alibris ID: 18393810195	Shipping Options: Standard Shipping: $4.99 Choose your shipping method in Checkout. Costs may vary based on destination.
  Seller's Description: New. Sewn binding. Paper over boards. 209 p. Contains: Illustrations, black & white, Illustrations, color, Line drawings, black & white, Line drawings, color, Tables, black & white, Figures. Advances and Technical Standards in Neurosurgery, 34. In Stock. 100% Money Back Guarantee. Brand New, Perfect Condition, allow 4-14 business days for standard shipping. To Alaska, Hawaii, U.S. protectorate, P.O. box, and APO/FPO addresses allow 4-28 business days for Standard shipping. No expedited shipping. All orders placed with expedited shipping will be cancelled. Over 3, 000, 000 happy customers.
  ► Contact This Seller
  Hide Details ▴

• Hardcover, New 2009, Springer ISBN-13: 9783211787403 See Item Details ▾

  Media Smart HIGH Hawthorne, CA, USA

  $151.19 $240.00 Add to Cart Add this copy of Advances and Technical Standards in Neurosurgery to cart. $151.19, new condition, Sold by Media Smart rated 4.0 out of 5 stars, ships from Hawthorne, CA, UNITED STATES, published 2009 by Springer.

  	Edition: 2009, Springer Hardcover, New	Details: ISBN: 3211787402 ISBN-13: 9783211787403 Pages: 209 Edition: 2009 edition Publisher: Springer Published: 2009 Language: English Alibris ID: 18326695833	Shipping Options: Standard Shipping: $4.99 Trackable Expedited: $9.99 Choose your shipping method in Checkout. Costs may vary based on destination.
  Seller's Description: New. P 206 1st Edition.
  ► Contact This Seller
  Hide Details ▴

• Trade paperback, New 2010, Springer ISBN-13: 9783211999295 See Item Details ▾

  Alibris BEST NV, USA

  $159.69 $219.99 Add to Cart Add this copy of Advances and Technical Standards in Neurosurgery: to cart. $159.69, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2010 by Springer.

  	Edition: 2010, Springer Trade paperback, New Available Copies: 10+	Details: ISBN: 3211999299 ISBN-13: 9783211999295 Pages: 209 Publisher: Springer Published: 2010 Language: English Alibris ID: 12174058684	Shipping Options: Standard Shipping: $4.99 Trackable Expedited: $9.99 Two Day Air: $29.99 Choose your shipping method in Checkout. Costs may vary based on destination.
  Seller's Description: New. Print on demand Trade paperback (US). Glued binding. 209 p. Advances and Technical Standards in Neurosurgery, 34.
  ► Contact This Seller
  Hide Details ▴

• Hardcover, New 2009, Springer ISBN-13: 9783211787403 See Item Details ▾

  Alibris BEST NV, USA

  $159.69 $240.00 Add to Cart Add this copy of Advances and Technical Standards in Neurosurgery: to cart. $159.69, new condition, Sold by Ingram Customer Returns Center rated 5.0 out of 5 stars, ships from NV, USA, published 2009 by Springer.

  	Edition: 2009, Springer Hardcover, New Available Copies: 10+	Details: ISBN: 3211787402 ISBN-13: 9783211787403 Pages: 209 Edition: 2009 edition Publisher: Springer Published: 2009 Language: English Alibris ID: 10625204209	Shipping Options: Standard Shipping: $4.99 Trackable Expedited: $9.99 Two Day Air: $29.99 Choose your shipping method in Checkout. Costs may vary based on destination.
  Seller's Description: New. Print on demand Sewn binding. Paper over boards. 209 p. Contains: Illustrations, black & white, Illustrations, color, Line drawings, black & white, Line drawings, color, Tables, black & white, Figures. Advances and Technical Standards in Neurosurgery, 34.
  ► Contact This Seller
  Hide Details ▴

• < Prev 1 2 Next >

2010, Springer, Vienna ISBN-13: 9783211999295 Trade paperback See All from $159.69

2009, Springer, Vienna ISBN-13: 9783211787403 2009 edition Hardcover See All from $149.67