Use of NSAIDs by systemic route may invoke the side effects as high dosages are required. By oral administration, the patient may suffer the side effects like gastrointestinal ulceration and intolerance, due to acidic nature of NSAIDs. Also by systemic route drug may be metabolized in liver. So drug loss will take place. Aceclofenac is a non steroidal anti-inflammatory drug which is a phenyl acetic acid derivative with effective anti-inflammatory and analgesic properties. It is a selective COX-2 inhibitor, mainly used for ...
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Use of NSAIDs by systemic route may invoke the side effects as high dosages are required. By oral administration, the patient may suffer the side effects like gastrointestinal ulceration and intolerance, due to acidic nature of NSAIDs. Also by systemic route drug may be metabolized in liver. So drug loss will take place. Aceclofenac is a non steroidal anti-inflammatory drug which is a phenyl acetic acid derivative with effective anti-inflammatory and analgesic properties. It is a selective COX-2 inhibitor, mainly used for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Transdermal drug administration was selected for Aceclofenac to avoid first pass metabolism in liver, to overcome the gastrointestinal irritation as drug is acidic in nature and to localize the drug at the disease site by the transdermal delivery of drug.
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Add this copy of Formulation and Evaluation of Aceclofenac Transdermal to cart. $98.60, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Santa Clarita, CA, UNITED STATES, published 2015 by LAP LAMBERT Academic Publishin.
