This book provides a unified and comprehensive compendium of issues related to the spinal delivery of drugs. The text, consisting of 34 chapters, begins with an extensive review of the early history, reflecting the development of the spinal cord as a route of spinal drug delivery. It then presents 4 principal divisions. In the first, the embryology, anatomy of the spinal canal, the spinal canal meninges and vasculature are reviewed in humans and non-human species. The second division considers the factors that define the ...
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This book provides a unified and comprehensive compendium of issues related to the spinal delivery of drugs. The text, consisting of 34 chapters, begins with an extensive review of the early history, reflecting the development of the spinal cord as a route of spinal drug delivery. It then presents 4 principal divisions. In the first, the embryology, anatomy of the spinal canal, the spinal canal meninges and vasculature are reviewed in humans and non-human species. The second division considers the factors that define the redistribution of spinally delivered drugs and the movements of such drugs into the spinal parenchyma are considered in detail. The third section considers issues that relate to the preclinical development of drugs for spinal delivery. This division includes issues that pertain to preclinical models for drug safety evaluation, the nature of vehicles for spinal drugs and properties of materials for chronic spinal implantation. In addition, the nature of the inflammatory reactions that are observed with foreign bodies and toxicity are presented. The fourth division considers the several therapeutic targets towards which spinally delivered drugs are aimed. These include analgesics, anesthetics, antispasticity, antimetastatic and growth factors. In each case, the site and mechanisms of action and the several drug classes that are relevant are presented. The book seeks to address the broad categories of interest that are represented by the scientists who focus on the biology of spinal cord function, the toxicologist and chemist who develop and formulate drugs for human spinal therapeutic use and the clinicians who seek an in-depth review of spinal drug delivery.
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Add this copy of Spinal Drug Delivery to cart. $68.11, good condition, Sold by HPB-Red rated 5.0 out of 5 stars, ships from Dallas, TX, UNITED STATES, published 1999 by Elsevier.
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Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority!
Add this copy of Spinal Drug Delivery to cart. $68.34, very good condition, Sold by Friends Tucson rated 5.0 out of 5 stars, ships from Tucson, AZ, UNITED STATES, published 1999 by Elsevier.
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Hardcover. NOT Ex-library. Very good condition. Clean pages and tight binding. Appears unread. Until further notice, USPS Priority Mail only reliable option for Hawaii. Proceeds benefit the Pima County Public Library system, which serves Tucson and southern Arizona.
Add this copy of Spinal Drug Delivery to cart. $68.59, good condition, Sold by HPB-Red rated 5.0 out of 5 stars, ships from Dallas, TX, UNITED STATES, published 1999 by Elsevier.
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Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority!
Add this copy of Spinal Drug Delivery to cart. $71.00, good condition, Sold by BookHouse On-Line rated 5.0 out of 5 stars, ships from Minneapolis, MN, UNITED STATES, published 1999 by Elsevier.
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Good. Size: 10x7x1; Highlighting to a few chapters: a nice reading/study copy. Binding tight and sturdy. Light wear to covers, bumped at corners. NOT ex-lib. No dust jacket, probably as issued. Due to the size/weight of this book extra charges may apply for international shipping. Not available for priority/expedited shipping. Ships from Dinkytown in Minneapolis, Minnesota.
Add this copy of Spinal Drug Delivery to cart. $118.27, good condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Santa Clarita, CA, UNITED STATES, published 1999 by Elsevier.
Add this copy of Spinal Drug Delivery to cart. $134.14, new condition, Sold by Media Smart rated 4.0 out of 5 stars, ships from Hawthorne, CA, UNITED STATES, published 1999 by Elsevier.
Add this copy of Spinal Drug Delivery to cart. $136.32, new condition, Sold by GridFreed rated 4.0 out of 5 stars, ships from North Las Vegas, NV, UNITED STATES, published 1999 by Elsevier.
Add this copy of Spinal Drug Delivery to cart. $182.46, new condition, Sold by discount_scientific_books rated 5.0 out of 5 stars, ships from Sterling Heights, MI, UNITED STATES, published 1999 by Elsevier.
Add this copy of Spinal Drug Delivery to cart. $221.78, new condition, Sold by Bonita rated 4.0 out of 5 stars, ships from Santa Clarita, CA, UNITED STATES, published 1999 by Elsevier.
